Role of TGF-β1 in renal parenchymal scarring following childhood urinary tract infection

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منابع مشابه

Risk Factors for Recurrent Urinary Tract Infection and Renal Scarring.

OBJECTIVES To identify risk factors for recurrent urinary tract infection (UTI) and renal scarring in children who have had 1 or 2 febrile or symptomatic UTIs and received no antimicrobial prophylaxis. METHODS This 2-year, multisite prospective cohort study included 305 children aged 2 to 71 months with vesicoureteral reflux (VUR) receiving placebo in the RIVUR (Randomized Intervention for Ve...

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Primary vesicoureteral reflux mediated renal scarring after urinary tract infection in Thai children.

AIM To evaluate the association between primary vesicoureteral reflux (VUR) and renal scarring in children using 99 m Technetium-labelled dimercaptosuccinic acid (DMSA). METHODS Children attending at Songklanagarind Hospital from 1987 to 2002 were evaluated. RESULTS Ages at diagnosis of VUR in 46 boys and 52 girls were 1.1+/-1.6 and 2.9+/-2.5 years, median 0.6 and 2.3 years, respectively (P...

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Risk assessment of renal cortical scarring with urinary tract infection by clinical features and ultrasonography.

AIMS To address some of the issues in the ongoing debate over the optimal diagnostic imaging following childhood urinary tract infection (UTI), by determining the risk of missing renal cortical scarring which would be detected on a technetium-99m dimercaptosuccinic acid (DMSA) gold standard if ultrasound alone were used, factoring for clinical features (upper or lower tract), UTI recurrence, an...

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Sex differences in childhood urinary tract infection.

Bergstrom, T. (1972). Archives of Disease in Childhood, 47, 227. Sex differences in childhood urinary tract infection. Comparison of the clinical picture of nonobstructed urinary tract infection in boys and in girls over the age of 1 year revealed marked differences. The male infections were characterized by a high rate of 'atypical' bacterial aetiology, macroscopical haematuria, and normal tem...

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The relationships between clinical variables and renal parenchymal disease in pediatric clinically suspected urinary tract infection

Urinary tract infection (UTI) is a common bacterial infection identified in young, febrile children. UTI may be limited to the bladder (cystitis) or can also involve the renal parenchyma (pyelonephritis). The clinical presentation of UTI may be non-specific and varies depending on factors such as the age of the child and the severity of infection. Accurate diagnosis based on clinical presentati...

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ژورنال

عنوان ژورنال: Kidney International

سال: 2002

ISSN: 0085-2538

DOI: 10.1046/j.1523-1755.2002.00110.x